Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 5' and Ligand = 'BDBM50256160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human))	BDBM50256160 (CHEMBL481896 | N-((5-bromo-8-hydroxyquinolin-7-yl)...) Show SMILES Oc1c(cc(Br)c2cccnc12)C(NC(=O)COc1ccccc1)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C24H18BrN3O5/c25-20-13-19(24(30)23-18(20)10-5-11-26-23)22(15-6-4-7-16(12-15)28(31)32)27-21(29)14-33-17-8-2-1-3-9-17/h1-13,22,30H,14H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5 by FRET assay				Bioorg Med Chem Lett 18: 6454-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.065 BindingDB Entry DOI: 10.7270/Q25H7G34
					More data for this Ligand-Target Pair