Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 5' and Ligand = 'BDBM50256499'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human))	BDBM50256499 (2-(4-chlorophenoxy)-N-((5-chloro-8-hydroxyquinolin...) Show SMILES Oc1c(cc(Cl)c2cccnc12)C(NC(=O)COc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C24H18Cl2N2O3/c25-16-8-10-17(11-9-16)31-14-21(29)28-22(15-5-2-1-3-6-15)19-13-20(26)18-7-4-12-27-23(18)24(19)30/h1-13,22,30H,14H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5 by FRET assay				Bioorg Med Chem Lett 18: 6454-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.065 BindingDB Entry DOI: 10.7270/Q25H7G34
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