Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 5' and Ligand = 'BDBM50256698'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human))	BDBM50256698 (2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...) Show SMILES Cc1cc(NCC(=O)NC(c2cccc(c2)[N+]([O-])=O)c2cc(Cl)c3cccnc3c2O)ccc1Cl Show InChI InChI=1S/C25H20Cl2N4O4/c1-14-10-16(7-8-20(14)26)29-13-22(32)30-23(15-4-2-5-17(11-15)31(34)35)19-12-21(27)18-6-3-9-28-24(18)25(19)33/h2-12,23,29,33H,13H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5 by FRET assay				Bioorg Med Chem Lett 18: 6454-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.065 BindingDB Entry DOI: 10.7270/Q25H7G34
					More data for this Ligand-Target Pair