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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM471794'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
A disintegrin and metalloproteinase with thrombospondin motifs 6


(Human)		BDBM471794
PNG
(5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) piperaz...)
Show SMILES COc1cc(cc(F)c1F)N1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r|
Show InChI InChI=1S/C19H24F2N4O4/c1-11(10-19(2)17(27)22-18(28)23-19)16(26)25-6-4-24(5-7-25)12-8-13(20)15(21)14(9-12)29-3/h8-9,11H,4-7,10H2,1-3H3,(H2,22,23,27,28)/t11-,19+/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 12.5n/an/an/an/an/an/a



GALAPAGOS NV

US Patent


Assay Description
TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...

US Patent US10829478 (2020)


BindingDB Entry DOI: 10.7270/Q2X351H2
More data for this
Ligand-Target Pair