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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ADAMTS5' and Ligand = 'BDBM471834'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ADAMTS5


(Rattus norvegicus (Rat))		BDBM471834
PNG
((5S)-5-[(2S)-3-[4- (3,4-difluoro-5- methoxy- pheny...)
Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCN(CC2)c2cc(F)c(F)c(OC)c2)NC(=O)NC1=O |r|
Show InChI InChI=1S/C20H26F2N4O5/c1-12(10-20(11-30-2)18(28)23-19(29)24-20)17(27)26-6-4-25(5-7-26)13-8-14(21)16(22)15(9-13)31-3/h8-9,12H,4-7,10-11H2,1-3H3,(H2,23,24,28,29)/t12-,20-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12.5n/an/an/an/an/an/a



GALAPAGOS NV

US Patent


Assay Description
TABLE VII: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H...

US Patent US10829478 (2020)


BindingDB Entry DOI: 10.7270/Q2X351H2
More data for this
Ligand-Target Pair