Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor/Nucleophosmin (Homo sapiens (Human)) | BDBM107057 (US8592432, 34) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-... | Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.049 BindingDB Entry DOI: 10.7270/Q2XS603J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor/Nucleophosmin (Homo sapiens (Human)) | BDBM107057 (US8592432, 34) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growth | Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.049 BindingDB Entry DOI: 10.7270/Q2XS603J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor/Nucleophosmin (Homo sapiens (Human)) | BDBM107057 (US8592432, 34) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition NMP-ALK (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmcl.2015.11.049 BindingDB Entry DOI: 10.7270/Q2XS603J | |||||||||||
More data for this Ligand-Target Pair |