Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM125911'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM125911 (US8765727, 14) Show SMILES Clc1cnc2Nc3cccc(CCCOc4ccc(Br)c(CNc1n2)c4)c3 Show InChI InChI=1S/C20H18BrClN4O/c21-17-7-6-16-10-14(17)11-23-19-18(22)12-24-20(26-19)25-15-5-1-3-13(9-15)4-2-8-27-16/h1,3,5-7,9-10,12H,2,4,8,11H2,(H2,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	7.8	n/a
Incyte Corporation US Patent					Assay Description HTRF kinase assay: 40 μL reactions were run in black 384 well polystyrene plates in assay buffer (50 mM Tris, pH 7.8, 100 mM NaCI, 0.1 mg/mL BSA...				US Patent US8765727 (2014) BindingDB Entry DOI: 10.7270/Q2FQ9V87
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