Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM179065'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM179065 (US9126931, 760) Show SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2cc(OC3CCOCC3)c(cc12)N1CCN(CC1)C1CCC1)C#N Show InChI InChI=1S/C32H36N4O3/c1-32(2)25-18-27(36-12-10-35(11-13-36)21-4-3-5-21)28(39-22-8-14-38-15-9-22)17-24(25)30(37)29-23-7-6-20(19-33)16-26(23)34-31(29)32/h6-7,16-18,21-22,34H,3-5,8-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha US Patent					Assay Description ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...				US Patent US9126931 (2015) BindingDB Entry DOI: 10.7270/Q22J69N8
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