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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM261649'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ALK tyrosine kinase receptor


(Homo sapiens (Human))		BDBM261649
PNG
(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Show SMILES CC(C)[Si](C#Cc1cccc(c1)-c1csc(NC(=O)c2ccc(o2)-c2ccc(cc2)C(=O)N2CCN(C)CC2)n1)(C(C)C)C(C)C
Show InChI InChI=1S/C37H44N4O3SSi/c1-25(2)46(26(3)4,27(5)6)22-17-28-9-8-10-31(23-28)32-24-45-37(38-32)39-35(42)34-16-15-33(44-34)29-11-13-30(14-12-29)36(43)41-20-18-40(7)19-21-41/h8-16,23-27H,18-21H2,1-7H3,(H,38,39,42)
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 420n/an/an/an/a7.525



UNIVERSITÁ DEGLI STUDI DI MILANO—BICOCCA; UNIVERSITÈ DE GENÈVE; UNIVERSITÈ CLAUDE BERNARD LYON 1

US Patent


Assay Description
GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...

US Patent US9708279 (2017)


BindingDB Entry DOI: 10.7270/Q2MC921P
More data for this
Ligand-Target Pair