Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50363249'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50363249 (CHEMBL1946800) Show SMILES CC(C)S(=O)(=O)c1ccc2CCc3cc(Nc4ncc(Cl)c(Nc1c2)n4)ccc3N1CCN(C)CC1 Show InChI InChI=1S/C26H31ClN6O2S/c1-17(2)36(34,35)24-9-5-18-4-6-19-15-20(7-8-23(19)33-12-10-32(3)11-13-33)29-26-28-16-21(27)25(31-26)30-22(24)14-18/h5,7-9,14-17H,4,6,10-13H2,1-3H3,(H2,28,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of baculovirus expressed GST-tagged human ALK cytoplasmic domain using PLCgamma as substrate after 15 mins by time-resolved fluorescence a...				J Med Chem 55: 449-64 (2012) Article DOI: 10.1021/jm201333e BindingDB Entry DOI: 10.7270/Q2BP0370
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50363249 (CHEMBL1946800) Show SMILES CC(C)S(=O)(=O)c1ccc2CCc3cc(Nc4ncc(Cl)c(Nc1c2)n4)ccc3N1CCN(C)CC1 Show InChI InChI=1S/C26H31ClN6O2S/c1-17(2)36(34,35)24-9-5-18-4-6-19-15-20(7-8-23(19)33-12-10-32(3)11-13-33)29-26-28-16-21(27)25(31-26)30-22(24)14-18/h5,7-9,14-17H,4,6,10-13H2,1-3H3,(H2,28,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of NPM-ALK autophosphorylation in human ALCL SUP-M2 cells after 2 to 3 hrs by sandwich ELISA				J Med Chem 55: 449-64 (2012) Article DOI: 10.1021/jm201333e BindingDB Entry DOI: 10.7270/Q2BP0370
					More data for this Ligand-Target Pair