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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AMSH-like protease' and Ligand = 'BDBM401021'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
AMSH-like protease


(Homo sapiens (Human))		BDBM401021
PNG
(US10005735, Compound 20)
Show SMILES Sc1cccc2cc(cnc12)C(=O)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C18H14N2O3S/c21-18(13-7-12-2-1-3-16(24)17(12)19-9-13)20-8-11-4-5-14-15(6-11)23-10-22-14/h1-7,9,24H,8,10H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<200n/an/an/an/an/an/a



Wyeth Research



Assay Description
In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...

Bioorg Med Chem 17: 8086-92 (2009)


BindingDB Entry DOI: 10.7270/Q22R3V09
More data for this
Ligand-Target Pair