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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP-4 complex subunit sigma-1' and Ligand = 'BDBM484121'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
AP-4 complex subunit sigma-1


(Homo sapiens (Human))		BDBM484121
PNG
(8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isobutyl-4- o...)
Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1
Show InChI InChI=1S/C21H32FN3O/c1-17(2)14-25-15-20(6-7-20)26-21(16-25)8-12-24(13-9-21)11-5-19-18(22)4-3-10-23-19/h3-4,10,17H,5-9,11-16H2,1-2H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
<100n/an/an/an/an/an/an/an/a



ESTEVE PHARMACEUTICALS. S.A.

US Patent


Assay Description
To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...

US Patent US10927128 (2021)


BindingDB Entry DOI: 10.7270/Q28918ZF
More data for this
Ligand-Target Pair