Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM321130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM321130 ((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6...) Show SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(N)cc-23)c1Cl |r| Show InChI InChI=1S/C19H24ClN3O2/c1-11(2)7-19(3,22)10-25-15-5-4-12-13-6-17(21)23-8-16(13)24-9-14(12)18(15)20/h4-6,8,11H,7,9-10,22H2,1-3H3,(H2,21,23)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10174044 (2019) BindingDB Entry DOI: 10.7270/Q2222WVN
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