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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DHX29' and Ligand = 'BDBM50283445'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DHX29


(Homo sapiens (Human))		BDBM50283445
PNG
(CHEMBL4175313)
Show SMILES FC(F)(F)c1cccc(c1)-c1cc(cn(-c2ccccc2)c1=O)C(=O)N1CCN([C@H](C1)c1ccc(Cl)cc1)C(=O)c1ccc(Br)cn1 |r|
Show InChI InChI=1S/C35H25BrClF3N4O3/c36-26-11-14-30(41-19-26)34(47)43-16-15-42(21-31(43)22-9-12-27(37)13-10-22)32(45)24-18-29(23-5-4-6-25(17-23)35(38,39)40)33(46)44(20-24)28-7-2-1-3-8-28/h1-14,17-20,31H,15-16,21H2/t31-/m1/s1
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...

ACS Med Chem Lett 8: 1077-1082 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00283
BindingDB Entry DOI: 10.7270/Q2QJ7KT3
More data for this
Ligand-Target Pair