BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50109810'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Mus musculus)		BDBM50109810
PNG
(2-(4-Diethylamino-phenyl)-3-[2-(6,7-dimethoxy-3,4-...)
Show SMILES CCN(CC)c1ccc(cc1)-c1nc2ccccc2c(=O)n1CCN1CCc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C31H36N4O3/c1-5-34(6-2)25-13-11-22(12-14-25)30-32-27-10-8-7-9-26(27)31(36)35(30)18-17-33-16-15-23-19-28(37-3)29(38-4)20-24(23)21-33/h7-14,19-20H,5-6,15-18,21H2,1-4H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Xenova Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.

Bioorg Med Chem Lett 12: 571-4 (2002)


BindingDB Entry DOI: 10.7270/Q2PV6JP9
More data for this
Ligand-Target Pair