Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM163804'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM163804 (US9062070, 59 | US9062070, 60) Show SMILES C[C@H]1Cc2cc(ccc2C(=O)O1)C1CN2CCN(CC2(C)CO1)C(=O)C1CCc2nc(ccc12)-n1cnnn1 |r| Show InChI InChI=1S/C28H31N7O4/c1-17-11-19-12-18(3-4-20(19)27(37)39-17)24-13-34-10-9-33(14-28(34,2)15-38-24)26(36)22-5-7-23-21(22)6-8-25(30-23)35-16-29-31-32-35/h3-4,6,8,12,16-17,22,24H,5,7,9-11,13-15H2,1-2H3/t17-,22?,24?,28?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9062070 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02JX
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM163804 (US9062070, 59 | US9062070, 60) Show SMILES C[C@H]1Cc2cc(ccc2C(=O)O1)C1CN2CCN(CC2(C)CO1)C(=O)C1CCc2nc(ccc12)-n1cnnn1 |r| Show InChI InChI=1S/C28H31N7O4/c1-17-11-19-12-18(3-4-20(19)27(37)39-17)24-13-34-10-9-33(14-28(34,2)15-38-24)26(36)22-5-7-23-21(22)6-8-25(30-23)35-16-29-31-32-35/h3-4,6,8,12,16-17,22,24H,5,7,9-11,13-15H2,1-2H3/t17-,22?,24?,28?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9062070 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02JX
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM163804 (US9062070, 59 | US9062070, 60) Show SMILES C[C@H]1Cc2cc(ccc2C(=O)O1)C1CN2CCN(CC2(C)CO1)C(=O)C1CCc2nc(ccc12)-n1cnnn1 |r| Show InChI InChI=1S/C28H31N7O4/c1-17-11-19-12-18(3-4-20(19)27(37)39-17)24-13-34-10-9-33(14-28(34,2)15-38-24)26(36)22-5-7-23-21(22)6-8-25(30-23)35-16-29-31-32-35/h3-4,6,8,12,16-17,22,24H,5,7,9-11,13-15H2,1-2H3/t17-,22?,24?,28?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9062070 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02JX
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM163804 (US9062070, 59 | US9062070, 60) Show SMILES C[C@H]1Cc2cc(ccc2C(=O)O1)C1CN2CCN(CC2(C)CO1)C(=O)C1CCc2nc(ccc12)-n1cnnn1 |r| Show InChI InChI=1S/C28H31N7O4/c1-17-11-19-12-18(3-4-20(19)27(37)39-17)24-13-34-10-9-33(14-28(34,2)15-38-24)26(36)22-5-7-23-21(22)6-8-25(30-23)35-16-29-31-32-35/h3-4,6,8,12,16-17,22,24H,5,7,9-11,13-15H2,1-2H3/t17-,22?,24?,28?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9062070 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02JX
					More data for this Ligand-Target Pair