Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM163839'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM163839 (US9062070, 94) Show SMILES Cc1c(cccc1[C@@H]1CN2CCN(C[C@@H]2CO1)C(=O)C1CCc2cc(ncc12)-n1cnnn1)[N+]#[C-] |r| Show InChI InChI=1S/C25H26N8O2/c1-16-19(4-3-5-22(16)26-2)23-13-31-8-9-32(12-18(31)14-35-23)25(34)20-7-6-17-10-24(27-11-21(17)20)33-15-28-29-30-33/h3-5,10-11,15,18,20,23H,6-9,12-14H2,1H3/t18-,20?,23+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9062070 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02JX
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