Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM194949'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM194949 (US9206198, 3) Show SMILES O=C1OCC(=C1)N1CCC2(CCN(CCc3ccc4C(=O)OCc4c3)CC2)C1=O |c:4| Show InChI InChI=1S/C22H24N2O5/c25-19-12-17(14-28-19)24-10-6-22(21(24)27)4-8-23(9-5-22)7-3-15-1-2-18-16(11-15)13-29-20(18)26/h1-2,11-12H,3-10,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.4	37
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM194949 (US9206198, 3) Show SMILES O=C1OCC(=C1)N1CCC2(CCN(CCc3ccc4C(=O)OCc4c3)CC2)C1=O |c:4| Show InChI InChI=1S/C22H24N2O5/c25-19-12-17(14-28-19)24-10-6-22(21(24)27)4-8-23(9-5-22)7-3-15-1-2-18-16(11-15)13-29-20(18)26/h1-2,11-12H,3-10,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair