Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM194959'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM194959 (US9206198, 13) Show SMILES CO[C@@H](CN1CCC2(CCN(C2=O)C2=C(C)C(=O)OC2C)CC1)c1ccc2C(=O)OCc2c1C |r,c:14| Show InChI InChI=1S/C26H32N2O6/c1-15-18(5-6-19-20(15)14-33-24(19)30)21(32-4)13-27-10-7-26(8-11-27)9-12-28(25(26)31)22-16(2)23(29)34-17(22)3/h5-6,17,21H,7-14H2,1-4H3/t17?,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	37
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks ...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM194959 (US9206198, 13) Show SMILES CO[C@@H](CN1CCC2(CCN(C2=O)C2=C(C)C(=O)OC2C)CC1)c1ccc2C(=O)OCc2c1C |r,c:14| Show InChI InChI=1S/C26H32N2O6/c1-15-18(5-6-19-20(15)14-33-24(19)30)21(32-4)13-27-10-7-26(8-11-27)9-12-28(25(26)31)22-16(2)23(29)34-17(22)3/h5-6,17,21H,7-14H2,1-4H3/t17?,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair