Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM196106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM196106 (US9206199, 11) Show SMILES Fc1ccc(C2CN3CCN(CC3CO2)C(=O)Cc2ccc(nc2)-n2cnnn2)c(F)c1[N+]#[C-] Show InChI InChI=1S/C22H20F2N8O2/c1-25-22-17(23)4-3-16(21(22)24)18-11-30-6-7-31(10-15(30)12-34-18)20(33)8-14-2-5-19(26-9-14)32-13-27-28-29-32/h2-5,9,13,15,18H,6-8,10-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9206199 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MND
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