Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM254070'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM254070 (US9493474, 2) Show SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(C1)CCN(C[C@H](O)c1ccc3C(=O)OCc3c1C)CC2 |r| Show InChI InChI=1S/C30H36N2O6/c1-18-20(3-5-22-24(18)15-37-28(22)35)26(33)13-31-10-7-30(8-11-31)9-12-32(17-30)14-27(34)21-4-6-23-25(19(21)2)16-38-29(23)36/h3-6,26-27,33-34H,7-17H2,1-2H3/t26-,27-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9493474 (2016) BindingDB Entry DOI: 10.7270/Q2GT5M3X
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