Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM290059'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM290059 (US9573961, Example 44 | US9573961, Example 74) Show SMILES Cc1c(ccc(F)c1C#N)[C@H]1CN2CCN(C[C@H]2CO1)C(=O)C1Cc2ccc(cc2C1)-n1cnnn1 |r| Show InChI InChI=1S/C26H26FN7O2/c1-16-22(4-5-24(27)23(16)11-28)25-13-32-6-7-33(12-21(32)14-36-25)26(35)19-8-17-2-3-20(10-18(17)9-19)34-15-29-30-31-34/h2-5,10,15,19,21,25H,6-9,12-14H2,1H3/t19?,21-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9573961 (2017) BindingDB Entry DOI: 10.7270/Q241704N
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM290059 (US9573961, Example 44 | US9573961, Example 74) Show SMILES Cc1c(ccc(F)c1C#N)[C@H]1CN2CCN(C[C@H]2CO1)C(=O)C1Cc2ccc(cc2C1)-n1cnnn1 |r| Show InChI InChI=1S/C26H26FN7O2/c1-16-22(4-5-24(27)23(16)11-28)25-13-32-6-7-33(12-21(32)14-36-25)26(35)19-8-17-2-3-20(10-18(17)9-19)34-15-29-30-31-34/h2-5,10,15,19,21,25H,6-9,12-14H2,1H3/t19?,21-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9573961 (2017) BindingDB Entry DOI: 10.7270/Q241704N
					More data for this Ligand-Target Pair