Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM312671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM312671 (US9604998, Example 70) Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN2C[C@@H](OC[C@@H]2C1)c1ccc2C(=O)OCc2c1 |r| Show InChI InChI=1S/C26H28N2O5/c1-16-17(2-5-22-23(16)15-33-26(22)30)6-7-27-8-9-28-12-24(31-14-20(28)11-27)18-3-4-21-19(10-18)13-32-25(21)29/h2-5,10,20,24H,6-9,11-15H2,1H3/t20-,24+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9604998 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MWK
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