Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM312677'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM312677 (US9604998, Example 76) Show SMILES COc1cc(ccc1C#N)[C@@H]1CN2CCN(CCc3ccc4C(=O)OCc4c3C)C[C@@H]2CO1 |r| Show InChI InChI=1S/C26H29N3O4/c1-17-18(5-6-22-23(17)16-33-26(22)30)7-8-28-9-10-29-14-25(32-15-21(29)13-28)19-3-4-20(12-27)24(11-19)31-2/h3-6,11,21,25H,7-10,13-16H2,1-2H3/t21-,25+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9604998 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MWK
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