Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM312681'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM312681 (US9604998, Example 80) Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN2C[C@H](OC[C@@H]2C1)c1ccc(F)c([N+]#[C-])c1C |r| Show InChI InChI=1S/C26H28FN3O3/c1-16-18(4-5-21-22(16)15-33-26(21)31)8-9-29-10-11-30-13-24(32-14-19(30)12-29)20-6-7-23(27)25(28-3)17(20)2/h4-7,19,24H,8-15H2,1-2H3/t19-,24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9604998 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MWK
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