Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM312706'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM312706 (US9604998, Example 105) Show SMILES Cc1c(ccc(F)c1[N+]#[C-])[C@@H]1CN2CCN(CCc3ccc4C(=O)OCc4c3)C[C@@H]2CN1 |r| Show InChI InChI=1S/C25H27FN4O2/c1-16-20(5-6-22(26)24(16)27-2)23-14-30-10-9-29(13-19(30)12-28-23)8-7-17-3-4-21-18(11-17)15-32-25(21)31/h3-6,11,19,23,28H,7-10,12-15H2,1H3/t19-,23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9604998 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MWK
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