Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM363479'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM363479 ((S)-4-(9-(2-(6-(1H-tetrazol-1- yl)pyridin-3-yl)-2-...) Show SMILES O[C@H](CN1CCC2(CC1)CN(CCO2)C1=CC(=O)OC1)c1ccc(nc1)-n1cnnn1 |r,t:16| Show InChI InChI=1S/C20H25N7O4/c28-17(15-1-2-18(21-10-15)27-14-22-23-24-27)11-25-5-3-20(4-6-25)13-26(7-8-31-20)16-9-19(29)30-12-16/h1-2,9-10,14,17,28H,3-8,11-13H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...				US Patent US9850245 (2017) BindingDB Entry DOI: 10.7270/Q2H70J3N
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