Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2' and Ligand = 'BDBM138755'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM138755 (US8877741, 2.81) Show SMILES C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(C2)c2ccnc(OCC3CC3)c2)cc1 |r| Show InChI InChI=1S/C23H27F2N3O3/c1-15(27-23(29)22(24)25)17-4-6-19(7-5-17)31-20-9-11-28(13-20)18-8-10-26-21(12-18)30-14-16-2-3-16/h4-8,10,12,15-16,20,22H,2-3,9,11,13-14H2,1H3,(H,27,29)/t15-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US8877741 (2014) BindingDB Entry DOI: 10.7270/Q2R78CXJ
					More data for this Ligand-Target Pair