Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM234353 (2,3,8,9,10,11-Hexahydro-benzothieno[3,2-e]imidazo[...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.32E+3 | -33.6 | 1.75E+3 | n/a | n/a | n/a | n/a | 7.3 | 25 |
University of Bonn | Assay Description Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch... | J Enzyme Inhib Med Chem 26: 350-8 (2011) Article DOI: 10.3109/14756366.2010.504674 BindingDB Entry DOI: 10.7270/Q2959GF5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM234353 (2,3,8,9,10,11-Hexahydro-benzothieno[3,2-e]imidazo[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | 7.3 | 25 |
University of Bonn | Assay Description Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch... | J Enzyme Inhib Med Chem 26: 350-8 (2011) Article DOI: 10.3109/14756366.2010.504674 BindingDB Entry DOI: 10.7270/Q2959GF5 | |||||||||||
More data for this Ligand-Target Pair |