BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM50240416'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysis				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 mins				Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	333	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of electric eel AChE by concentration-dependent inhibition assay				Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV
The University of Montana Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	567	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of rat brain AChE by time-dependent inhibition assay				Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV
The University of Montana Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	267	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of rat brain AChE by concentration-dependent inhibition assay				Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV
The University of Montana Curated by ChEMBL					More data for this Ligand-Target Pair