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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid ceramidase' and Ligand = 'BDBM50431256'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acid ceramidase


(Rattus norvegicus (Rat))		BDBM50431256
PNG
(CHEMBL2333052)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)C(C)C)c1=O
Show InChI InChI=1S/C15H22FN3O4/c1-4-5-6-7-8-17-14(22)18-9-11(16)13(21)19(15(18)23)12(20)10(2)3/h9-10H,4-8H2,1-3H3,(H,17,22)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...

J Med Chem 56: 3518-30 (2013)


Article DOI: 10.1021/jm301879g
BindingDB Entry DOI: 10.7270/Q27D2WH5
More data for this
Ligand-Target Pair