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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acrosin' and Ligand = 'BDBM50382089'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acrosin


(Homo sapiens (Human))		BDBM50382089
PNG
(CHEMBL2022135)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)Nc1cc(C)ccc1C
Show InChI InChI=1S/C17H18N4O4S/c1-10-4-5-11(2)14(8-10)21-26(23,24)12-6-7-13-15(9-12)19-16(18-13)20-17(22)25-3/h4-9,21H,1-3H3,(H2,18,19,20,22)
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Article
PubMed
n/an/a 8.86E+6n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry

Bioorg Med Chem Lett 22: 3554-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.042
BindingDB Entry DOI: 10.7270/Q2HT2QBG
More data for this
Ligand-Target Pair