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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50040818'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50040818
PNG
(2-Chloro-6,11-dihydro-dibenzo[b,e]oxepine-11-carbo...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)C1c2ccccc2COc2ccc(Cl)cc12
Show InChI InChI=1S/C27H28ClNO2/c1-16(2)20-10-7-11-21(17(3)4)26(20)29-27(30)25-22-9-6-5-8-18(22)15-31-24-13-12-19(28)14-23(24)25/h5-14,16-17,25H,15H2,1-4H3,(H,29,30)
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Kyowa Hakko Kogyo Company

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits

J Med Chem 37: 804-10 (1994)


BindingDB Entry DOI: 10.7270/Q20C4TTM
More data for this
Ligand-Target Pair