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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50040829'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50040829
PNG
(2-Methyl-6,11-dihydro-dibenzo[b,e]oxepine-11-carbo...)
Show SMILES Cc1ccc2OCc3ccccc3C(C(=O)Nc3c(C)cc(C)cc3C)c2c1
Show InChI InChI=1S/C25H25NO2/c1-15-9-10-22-21(13-15)23(20-8-6-5-7-19(20)14-28-22)25(27)26-24-17(3)11-16(2)12-18(24)4/h5-13,23H,14H2,1-4H3,(H,26,27)
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n/an/a 110n/an/an/an/an/an/a



Kyowa Hakko Kogyo Company

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits

J Med Chem 37: 804-10 (1994)


BindingDB Entry DOI: 10.7270/Q20C4TTM
More data for this
Ligand-Target Pair