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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50040837'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50040837
PNG
(2-Methoxy-6,11-dihydro-dibenzo[b,e]oxepine-11-carb...)
Show SMILES COc1ccc2OCc3ccccc3C(C(=O)Nc3c(cccc3C(C)C)C(C)C)c2c1
Show InChI InChI=1S/C28H31NO3/c1-17(2)21-11-8-12-22(18(3)4)27(21)29-28(30)26-23-10-7-6-9-19(23)16-32-25-14-13-20(31-5)15-24(25)26/h6-15,17-18,26H,16H2,1-5H3,(H,29,30)
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n/an/a 140n/an/an/an/an/an/a



Kyowa Hakko Kogyo Company

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits

J Med Chem 37: 804-10 (1994)


BindingDB Entry DOI: 10.7270/Q20C4TTM
More data for this
Ligand-Target Pair