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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50040843'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50040843
PNG
(2-Bromo-6,11-dihydro-dibenzo[b,e]oxepine-11-carbox...)
Show SMILES Clc1cccc(Cl)c1NC(=O)C1c2ccccc2COc2ccc(Br)cc12
Show InChI InChI=1S/C21H14BrCl2NO2/c22-13-8-9-18-15(10-13)19(14-5-2-1-4-12(14)11-27-18)21(26)25-20-16(23)6-3-7-17(20)24/h1-10,19H,11H2,(H,25,26)
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n/an/a 74n/an/an/an/an/an/a



Kyowa Hakko Kogyo Company

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits

J Med Chem 37: 804-10 (1994)


BindingDB Entry DOI: 10.7270/Q20C4TTM
More data for this
Ligand-Target Pair