Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047508'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047508 (1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-2-me...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cc(nc2C)-c2ccc(OC)cc2)cccc1N(C)C Show InChI InChI=1S/C28H39N5O3/c1-6-7-8-17-29-28(34)31-27-25(32(3)4)11-9-12-26(27)36-19-10-18-33-20-24(30-21(33)2)22-13-15-23(35-5)16-14-22/h9,11-16,20H,6-8,10,17-19H2,1-5H3,(H2,29,31,34)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047508 (1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-2-me...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cc(nc2C)-c2ccc(OC)cc2)cccc1N(C)C Show InChI InChI=1S/C28H39N5O3/c1-6-7-8-17-29-28(34)31-27-25(32(3)4)11-9-12-26(27)36-19-10-18-33-20-24(30-21(33)2)22-13-15-23(35-5)16-14-22/h9,11-16,20H,6-8,10,17-19H2,1-5H3,(H2,29,31,34)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair