Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047544'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047544 (1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1C(C)C Show InChI InChI=1S/C28H38N4O2/c1-5-6-10-17-29-28(33)31-27-24(21(2)3)15-11-16-25(27)34-19-12-18-32-20-30-26(22(32)4)23-13-8-7-9-14-23/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047544 (1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1C(C)C Show InChI InChI=1S/C28H38N4O2/c1-5-6-10-17-29-28(33)31-27-24(21(2)3)15-11-16-25(27)34-19-12-18-32-20-30-26(22(32)4)23-13-8-7-9-14-23/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair