Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adenomatous polyposis coli protein' and Ligand = 'BDBM275757'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenomatous polyposis coli protein (Homo sapiens (Human))	BDBM275757 (US10071086, Compound 785) Show SMILES CCC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cccc4[nH]3)-c3ccsc3)c2c1 Show InChI InChI=1S/C25H19N7OS/c1-2-21(33)28-17-8-15(10-26-12-17)16-9-19-23(31-32-24(19)27-11-16)25-29-20-5-3-4-18(22(20)30-25)14-6-7-34-13-14/h3-13H,2H2,1H3,(H,28,33)(H,29,30)(H,27,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...				US Patent US10071086 (2018) BindingDB Entry DOI: 10.7270/Q2SF2Z68
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