BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50001493'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 330: 212-21 (1985) Article DOI: 10.1007/bf00572436 BindingDB Entry DOI: 10.7270/Q2RB7334
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 330: 212-21 (1985) Article DOI: 10.1007/bf00572436 BindingDB Entry DOI: 10.7270/Q2RB7334
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by PDSP K_i Database									Mol Pharmacol 29: 331-46 (1986) BindingDB Entry DOI: 10.7270/Q2MK6BDV
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by PDSP K_i Database									Mol Pharmacol 56: 705-13 (1999) BindingDB Entry DOI: 10.7270/Q2M9077B
University of Virginia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmazeutische Chemie Curated by ChEMBL					Assay Description Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligand				J Med Chem 36: 3341-9 (1993) BindingDB Entry DOI: 10.7270/Q26Q1W9W
Pharmazeutische Chemie Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CV Therapeutics Inc. Curated by ChEMBL					Assay Description Displacement of [3H]CPX from human adenosine A3 receptor expressed in CHO cells				J Med Chem 49: 3682-92 (2006) Article DOI: 10.1021/jm051268+ BindingDB Entry DOI: 10.7270/Q21V5DMG
CV Therapeutics Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Binding affinity to human adenosine A1 receptor				J Med Chem 52: 3994-4006 (2009) Article DOI: 10.1021/jm900413e BindingDB Entry DOI: 10.7270/Q24J0G1M
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity for Adenosine A1 receptor from rat brain using [3H]-PIA as radioligand				J Med Chem 33: 2818-21 (1990) BindingDB Entry DOI: 10.7270/Q2C53JVQ
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (GUINEA PIG)	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Affinity against adenosine A1 receptor in the brain membranes by the displacement of [3H]-CPX.				J Med Chem 35: 4039-44 (1992) BindingDB Entry DOI: 10.7270/Q2CF9P23
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (GUINEA PIG)	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor of cerebral cortex using [3H]-CPX as a radioligand				J Med Chem 36: 1380-6 (1993) BindingDB Entry DOI: 10.7270/Q23B5Z65
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranes				J Med Chem 32: 1231-7 (1989) BindingDB Entry DOI: 10.7270/Q2PZ57T1
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50001493 (3-Propyl-3,7-dihydro-purine-2,6-dione \| 3-Propyl-3...) Show SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.56E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Binding affinity to rat adenosine A1 receptor				J Med Chem 52: 3994-4006 (2009) Article DOI: 10.1021/jm900413e BindingDB Entry DOI: 10.7270/Q24J0G1M
Institute Curated by ChEMBL					More data for this Ligand-Target Pair