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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2b' and Ligand = 'BDBM50238389'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50238389
PNG
(CHEMBL4066559)
Show SMILES Nc1ccc(cc1)-n1nc2c(N)nc(cn2c1=O)-c1ccccc1
Show InChI InChI=1S/C17H14N6O/c18-12-6-8-13(9-7-12)23-17(24)22-10-14(11-4-2-1-3-5-11)20-15(19)16(22)21-23/h1-10H,18H2,(H2,19,20)
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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Antagonist activity at human adenosine receptor A2B expressed in CHO cell membranes assessed as inhibition of NECA-induced increase of cAMP accumulat...

J Med Chem 60: 5772-5790 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00457
BindingDB Entry DOI: 10.7270/Q21V5H87
More data for this
Ligand-Target Pair