BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with Target = 'Adenosine receptor A3' and Ligand = 'BDBM50207816'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A3 (Sheep)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	25.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]-IABA radioligand.				J Med Chem 43: 1165-72 (2000) BindingDB Entry DOI: 10.7270/Q2M044NW
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by PDSP K_i Database									Mol Pharmacol 57: 968-75 (2000) BindingDB Entry DOI: 10.7270/Q2CJ8C1K
University of Ferrara Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by PDSP K_i Database									Mol Pharmacol 57: 968-75 (2000) BindingDB Entry DOI: 10.7270/Q2CJ8C1K
University of Ferrara Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Binding affinity for human Adenosine A3 receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	70.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 90: 10365-9 (1993) Article DOI: 10.1073/pnas.90.21.10365 BindingDB Entry DOI: 10.7270/Q24Q7SH0
Merck Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	91.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Würzburg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 357: 1-9 (1998) Article DOI: 10.1007/pl00005131 BindingDB Entry DOI: 10.7270/Q20Z71T3
Universität Würzburg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NECA from human A3AR expressed in HeLa cell membrane incubated for 180 mins by microbeta trilux scintillation counter analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01636 BindingDB Entry DOI: 10.7270/Q2M61Q5K
TBA					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at wild-type Adenosine A3 receptor expressed in COS-7 cells				J Med Chem 44: 4125-36 (2001) BindingDB Entry DOI: 10.7270/Q2Z60PSZ
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells				J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Oryctolagus cuniculus (rabbit))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	329	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 280: 122-8 (1997) BindingDB Entry DOI: 10.7270/Q2J67FFH
Pfizer Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A3 (Rattus norvegicus)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	418	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at Mutant (H272E) human adenosine A3 receptor expressed in COS-7 cells				J Med Chem 44: 4125-36 (2001) BindingDB Entry DOI: 10.7270/Q2Z60PSZ
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of CELT-228 from human adenosine A3 receptor expressed in human HeLa cells incubated for 30 mins by fluorescence polarization binding as...				Bioorg Med Chem Lett 14: 4045-50 (2004) Article DOI: 10.1021/acsmedchemlett.1c00598 BindingDB Entry DOI: 10.7270/Q2J67MTH
Millennium Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Rattus norvegicus)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Displacement of [125I]-AB-MECA from membranes of CHO cells stably transfected with the rat adenosine A3 receptor cDNA				J Med Chem 37: 3373-82 (1994) BindingDB Entry DOI: 10.7270/Q28914WW
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	9.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells incubated for 30 mins by fluorescence polarization binding as...				Bioorg Med Chem Lett 14: 4045-50 (2004) Article DOI: 10.1021/acsmedchemlett.1c00598 BindingDB Entry DOI: 10.7270/Q2J67MTH
Millennium Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair