Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 8' and Ligand = 'BDBM50521100'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 8 (Homo sapiens (Human))	BDBM50521100 (CHEMBL4575792) Show SMILES Fc1ccc(cc1)-c1nnc(NC(=O)c2cccc(c2)-c2ccccc2)o1 Show InChI InChI=1S/C21H14FN3O2/c22-18-11-9-15(10-12-18)20-24-25-21(27-20)23-19(26)17-8-4-7-16(13-17)14-5-2-1-3-6-14/h1-13H,(H,23,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...				Eur J Med Chem 162: 568-585 (2019) Article DOI: 10.1016/j.ejmech.2018.11.036 BindingDB Entry DOI: 10.7270/Q23X8B2X
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