Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Advanced glycosylation end product-specific receptor' and Ligand = 'BDBM50005634'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50005634 (CHEMBL3235375) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C34H41FN4O4/c1-5-8-21-42-33-23-29(41-22-9-20-39(6-2)7-3)18-19-30(33)36-34(40)32-24-31(37-38(32)4)25-10-14-27(15-11-25)43-28-16-12-26(35)13-17-28/h10-19,23-24H,5-9,20-22H2,1-4H3,(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Woosuk University Curated by ChEMBL					Assay Description Inhibition of biotinylated human RAGE assessed as bound amyloid beta level after 60 mins by ELISA				Eur J Med Chem 79: 128-42 (2014) Article DOI: 10.1016/j.ejmech.2014.03.072 BindingDB Entry DOI: 10.7270/Q2C82BTF
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50005634 (CHEMBL3235375) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C34H41FN4O4/c1-5-8-21-42-33-23-29(41-22-9-20-39(6-2)7-3)18-19-30(33)36-34(40)32-24-31(37-38(32)4)25-10-14-27(15-11-25)43-28-16-12-26(35)13-17-28/h10-19,23-24H,5-9,20-22H2,1-4H3,(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50005634 (CHEMBL3235375) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C34H41FN4O4/c1-5-8-21-42-33-23-29(41-22-9-20-39(6-2)7-3)18-19-30(33)36-34(40)32-24-31(37-38(32)4)25-10-14-27(15-11-25)43-28-16-12-26(35)13-17-28/h10-19,23-24H,5-9,20-22H2,1-4H3,(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a
Woosuk University Curated by ChEMBL					Assay Description Binding affinity to biotinylated human RAGE by surface plasmon resonance analysis				Eur J Med Chem 79: 128-42 (2014) Article DOI: 10.1016/j.ejmech.2014.03.072 BindingDB Entry DOI: 10.7270/Q2C82BTF
					More data for this Ligand-Target Pair