Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Advanced glycosylation end product-specific receptor' and Ligand = 'BDBM50249568'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249568 (CHEMBL4068269) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)OCC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C47H60N4O5/c1-4-7-29-55-45-32-37(54-30-15-26-50(5-2)6-3)22-23-43(45)48-46(52)44(31-35-24-27-51(28-25-35)33-36-16-9-8-10-17-36)49-47(53)56-34-42-40-20-13-11-18-38(40)39-19-12-14-21-41(39)42/h8-14,16-23,32,35,42,44H,4-7,15,24-31,33-34H2,1-3H3,(H,48,52)(H,49,53)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of S110B binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249568 (CHEMBL4068269) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)OCC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C47H60N4O5/c1-4-7-29-55-45-32-37(54-30-15-26-50(5-2)6-3)22-23-43(45)48-46(52)44(31-35-24-27-51(28-25-35)33-36-16-9-8-10-17-36)49-47(53)56-34-42-40-20-13-11-18-38(40)39-19-12-14-21-41(39)42/h8-14,16-23,32,35,42,44H,4-7,15,24-31,33-34H2,1-3H3,(H,48,52)(H,49,53)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249568 (CHEMBL4068269) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)OCC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C47H60N4O5/c1-4-7-29-55-45-32-37(54-30-15-26-50(5-2)6-3)22-23-43(45)48-46(52)44(31-35-24-27-51(28-25-35)33-36-16-9-8-10-17-36)49-47(53)56-34-42-40-20-13-11-18-38(40)39-19-12-14-21-41(39)42/h8-14,16-23,32,35,42,44H,4-7,15,24-31,33-34H2,1-3H3,(H,48,52)(H,49,53)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair