Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Advanced glycosylation end product-specific receptor' and Ligand = 'BDBM50249569'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249569 (CHEMBL4063487) Show SMILES CCCCn1c(nc2cc(OCCCN(CC)CC)ccc12)[C@@H](Cc1ccc(OCCc2ccc(Cl)cc2)cc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C39H53ClN4O4/c1-7-10-24-44-36-21-20-33(46-25-11-23-43(8-2)9-3)28-34(36)41-37(44)35(42-38(45)48-39(4,5)6)27-30-14-18-32(19-15-30)47-26-22-29-12-16-31(40)17-13-29/h12-21,28,35H,7-11,22-27H2,1-6H3,(H,42,45)/t35-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of S110B binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249569 (CHEMBL4063487) Show SMILES CCCCn1c(nc2cc(OCCCN(CC)CC)ccc12)[C@@H](Cc1ccc(OCCc2ccc(Cl)cc2)cc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C39H53ClN4O4/c1-7-10-24-44-36-21-20-33(46-25-11-23-43(8-2)9-3)28-34(36)41-37(44)35(42-38(45)48-39(4,5)6)27-30-14-18-32(19-15-30)47-26-22-29-12-16-31(40)17-13-29/h12-21,28,35H,7-11,22-27H2,1-6H3,(H,42,45)/t35-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249569 (CHEMBL4063487) Show SMILES CCCCn1c(nc2cc(OCCCN(CC)CC)ccc12)[C@@H](Cc1ccc(OCCc2ccc(Cl)cc2)cc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C39H53ClN4O4/c1-7-10-24-44-36-21-20-33(46-25-11-23-43(8-2)9-3)28-34(36)41-37(44)35(42-38(45)48-39(4,5)6)27-30-14-18-32(19-15-30)47-26-22-29-12-16-31(40)17-13-29/h12-21,28,35H,7-11,22-27H2,1-6H3,(H,42,45)/t35-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair