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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50008470'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50008470
PNG
(CHEMBL357206 | [4-Oxo-3-(3-pyridin-2-yl-[1,2,4]oxa...)
Show SMILES OC(=O)Cc1nn(Cc2nc(no2)-c2ccccn2)c(=O)c2ccccc12
Show InChI InChI=1S/C18H13N5O4/c24-16(25)9-14-11-5-1-2-6-12(11)18(26)23(21-14)10-15-20-17(22-27-15)13-7-3-4-8-19-13/h1-8H,9-10H2,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 156n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against aldose reductase isolated from human placenta

J Med Chem 35: 457-65 (1992)


BindingDB Entry DOI: 10.7270/Q28051K1
More data for this
Ligand-Target Pair