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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50126782'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Rattus norvegicus)		BDBM50126782
PNG
((1-Benzyl-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl...)
Show SMILES OC(=O)C(C#N)C1C(=O)N(Cc2ccccc2)c2ccc(F)cc12
Show InChI InChI=1S/C18H13FN2O3/c19-12-6-7-15-13(8-12)16(14(9-20)18(23)24)17(22)21(15)10-11-4-2-1-3-5-11/h1-8,14,16H,10H2,(H,23,24)
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Università di Pisa

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.

J Med Chem 46: 1419-28 (2003)


Article DOI: 10.1021/jm030762f
BindingDB Entry DOI: 10.7270/Q21G0KN9
More data for this
Ligand-Target Pair