Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, germ cell type' and Ligand = 'BDBM396266'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, germ cell type (Homo sapiens (Human))	BDBM396266 (US10314827, Compound 7 | US10314827, Compound 8) Show SMILES C[C@@H]1[C@H]2[C@@H](C[C@H](C)CN2C(=O)OCc2ccccc2)O[C@]11CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC2=C(C)C1)OCc1ccccc1 |r,t:29,42| Show InChI InChI=1S/C43H55NO4/c1-28-21-39-40(44(25-28)41(45)47-27-32-13-9-6-10-14-32)30(3)43(48-39)20-18-35-36-16-15-33-22-34(46-26-31-11-7-5-8-12-31)17-19-42(33,4)38(36)23-37(35)29(2)24-43/h5-15,28,30,34-36,38-40H,16-27H2,1-4H3/t28-,30+,34-,35-,36-,38-,39+,40-,42-,43-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...				Bioorg Med Chem Lett 18: 1994-9 (2008) BindingDB Entry DOI: 10.7270/Q2QR50GW
					More data for this Ligand-Target Pair
Alkaline phosphatase, germ cell type (Homo sapiens (Human))	BDBM396266 (US10314827, Compound 7 | US10314827, Compound 8) Show SMILES C[C@@H]1[C@H]2[C@@H](C[C@H](C)CN2C(=O)OCc2ccccc2)O[C@]11CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC2=C(C)C1)OCc1ccccc1 |r,t:29,42| Show InChI InChI=1S/C43H55NO4/c1-28-21-39-40(44(25-28)41(45)47-27-32-13-9-6-10-14-32)30(3)43(48-39)20-18-35-36-16-15-33-22-34(46-26-31-11-7-5-8-12-31)17-19-42(33,4)38(36)23-37(35)29(2)24-43/h5-15,28,30,34-36,38-40H,16-27H2,1-4H3/t28-,30+,34-,35-,36-,38-,39+,40-,42-,43-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...				Bioorg Med Chem Lett 18: 1994-9 (2008) BindingDB Entry DOI: 10.7270/Q2QR50GW
					More data for this Ligand-Target Pair