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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, germ cell type' and Ligand = 'BDBM396269'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alkaline phosphatase, germ cell type


(Homo sapiens (Human))		BDBM396269
PNG
(US10314827, Compound 10)
Show SMILES CC(C)N1C[C@@H](C)C[C@H]2O[C@]3(CC[C@H]4[C@@H]5CC[C@@H]6CC(=O)CC[C@]6(C)[C@H]5CC4=C(C)C3)[C@H](C)[C@H]12 |r,t:30|
Show InChI InChI=1S/C31H49NO2/c1-18(2)32-17-19(3)13-28-29(32)21(5)31(34-28)12-10-24-25-8-7-22-14-23(33)9-11-30(22,6)27(25)15-26(24)20(4)16-31/h18-19,21-22,24-25,27-29H,7-17H2,1-6H3/t19-,21+,22+,24-,25-,27-,28+,29-,30-,31-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>100n/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...

Bioorg Med Chem Lett 18: 1994-9 (2008)


BindingDB Entry DOI: 10.7270/Q2QR50GW
More data for this
Ligand-Target Pair